0

Diagnostic Decision Support with Bayesian Networks

 

In this webinar, we will illustrate how Bayesian networks can serve as a practical tool for optimizing the sequence of diagnostic steps with the objective of arriving at a medical diagnosis in a quick and cost-efficient manner. Bayesian networks allow us to precisely quantify the amount of information contributed from each to-be-observed variable, such as risk factors and symptoms. This capability is one of the key points whereby machine-learned Bayesian networks distinguish themselves from other predictive models, e.g. neural networks.

We will utilize the dataset published by Dr. Zahra Alizadeh Sani on Coronary Artery Disease to demonstrate a complete research workflow, from importing the raw data all the way through publishing a final model with a web interface.

Workflow with the BayesiaLab Software Platform:

  • Data Import into BayesiaLab.
  • Discretization of continuous variables.
  • Definition of variable classes.
  • Supervised Learning using the Markov Blanket and Augmented Markov Blanket algorithms.
  • Structural Coefficient Analysis for Bayesian network model optimization.
  • Network Performance Analysis with regard to one or multiple Target Nodes (Stenosis of LAD, LCX, or RCA).
  • Introduction to information-theoretic concepts, such as Entropy and Mutual Information.
  • 2D Mapping to illustrate Mutual Information between variables and Target Nodes.
  • Computation of an interactive and dynamic Adaptive Questionnaire for optimized evidence-seeking with regard to the diagnosis.
  • Introduction of the cost of diagnostic procedures for optimization, i.e., trading off the cost of information gain vs. the expected reduction of uncertainty.
  • Computation of Target Interpretation Tree as a static decision support tool.
  • Publication of the Adaptive Questionnaire to the BayesiaLab WebSimulator as a decision support tool for external users.

References

Cardiovascular Imaging Department, Rajaei Cardiovascular, Medical & Research Center, Iran University, Tehran, Iran

Updated (Extended) Dataset:
https://www.researchgate.net/publication/311582821_extention_of_Z-Alizadeh_sani_dataset

Original (Limited) Dataset:
https://archive.ics.uci.edu/ml/datasets/Z-Alizadeh+Sani

Reply Oldest first
  • Oldest first
  • Newest first
  • Active threads
  • Popular
Like Follow
  • 5 mths agoLast active
  • 33Views
  • 1 Following